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Science 7 July 1967:
Vol. 157. no. 3784, pp. 73 - 75
DOI: 10.1126/science.157.3784.73
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Articles

Isoprenoid Biosynthesis in a Cell-Free System from Pea Shoots

Jan E. Graebe 1

1 Pflanzenphysiologisches Institut der Universität 34, Göttingen, Germany

A cell-free system consisting of a soluble fraction and plastid fragments from pea shoots incorporates 2-14C-mevalonate very actively into farnesol, squalene, geranylgeraniol, and other isoprenoids of different carbon-chain lengths. The products have different cofactor requirements, which makes it possible to channel the pathway into different products by varying the incubation mixture.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)