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Science 7 July 1967:
Vol. 157. no. 3784, pp. 69 - 70
DOI: 10.1126/science.157.3784.69
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Articles

Adenovirus Endocarditis in Mice

Z. R. Blailock 1, E. R. Rabin 1, and J. L. Melnick 1

1 Department of Pathology and Virology and Epidemiology, Baylor University College of Medicine, Houston, Texas 77025

Viral endocarditis developed in 24 percent of 50 newborn mice 6 to 8 days after intraperitoneal inoculation with murine adenovirus. Typical adenovirus intranuclear inclusions were seen in heart-valve lesions, and high titers of virus were recovered from heart tissue. Furthermore, adenovirions were directly visualized by electron microscopy within endothelial cells and fibroblasts of the heart valves.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Natural Pathogens of Laboratory Mice, Rats, and Rabbits and Their Effects on Research.
D. G. Baker (1998)
Clin. Microbiol. Rev. 11, 231-266
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Distribution of Mouse Adenovirus Type 1 in Intraperitoneally and Intranasally Infected Adult Outbred Mice.
A. E. Kajon, C. C. Brown, and K. R. Spindler (1998)
J. Virol. 72, 1219-1223
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Encephalomyocarditis Infection of the Newborn Mouse Myocardium: An Electron Microscopic Study.
G. E. Burch, J. M. Harb, H. L. Colcolough, and C.-Y. Tsui (1971)
Arch Intern Med 127, 148-156
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