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Science 23 June 1967:
Vol. 156. no. 3782, pp. 1628 - 1629
DOI: 10.1126/science.156.3782.1628
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Articles

Recurrent Herpes in the Rabbit and Man

Herbert E. Kaufman 1, David C. Brown 1, and Emily Maloney Ellison 1

1 Department of Ophthalmology, University of Florida, Gainesville 32601

Herpesvirus was present in secretory glands and frequently in tears of rabbits with recurrent herpetic keratitis even in the absence of corneal lesions. In normal people, herpesvirus could be cultured from saliva and tears. Chronic virus multiplication in structures such as the lacrimal and salivary glands, rather than latency, may cause recurrent herpetic disease.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
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Effect of Prophylactic Valacyclovir on the Presence of Human Herpesvirus DNA in Saliva of Healthy Individuals after Dental Treatment.
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HSV-1 DNA in Tears and Saliva of Normal Adults.
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Antigens of Herpes Simplex Virus in Whole Corneal Epithelial Sheets From Mice.
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Visceral Herpesvirus Infections in Leukemic Patients Receiving Cytarabine.
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Herpesvirus in Sensory and Autonomic Ganglia After Eye Infection: Absence of Chronic Viral Shedding.
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Arch Ophthalmol 95, 2053-2056
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Treatment of Labial Herpes.
G. R. Nugent and S. M. Chou (1973)
JAMA 224, 132
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Idoxuridine in Herpes Simplex Virus (Type 1) Encephalitis: Experience with 29 Cases in Michigan, 1966 to 1971.
D. C. NOLAN, C. B. LAUTER, and A. M. LERNER (1973)
Ann Intern Med 78, 243-246
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Latent Herpes Simplex Virus: Isolation From Rabbit Trigeminal Ganglia Between Episodes of Recurrent Ocular Infection.
A. B. Nesburn, M. L. Cook, and J. G. Stevens (1972)
Arch Ophthalmol 88, 412-417
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Penetrating Grafts Using Herpes Convalescent Cornea.
R. W. Darrell (1972)
Arch Ophthalmol 87, 411-416
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Cornea and Sclera.
P. R. Laibson (1970)
Arch Ophthalmol 83, 637-657
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Broadening Spectrum of Herpesvirus hominis (Herpes Simplex).
(1970)
Arch Dermatol 101, 364-366
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Chronic Herpes Simplex Infection of the Ocular Adnexa: Persistence of Virus in the Rabbit After Enucleation.
D. C. Brown and H. E. Kaufman (1969)
Arch Ophthalmol 81, 837-839
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Disseminated Herpes Simplex in a Newborn: A Consequence of Infection in the Mother.
A. W. Hudson and C. McFarland (1969)
JAMA 208, 859-861
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Herpes Simplex Virus in Mice: Electron Microscopy of Neural Spread.
E. R. Rabin, A. B. Jenson, and J. L. Melnick (1968)
Science 162, 126-127
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Recurrent Herpes Simplex of the Hard Palate: Case Report and Comment Concerning Reinfection and Rarity of Disease in the Mouth.
S. A. Muller (1968)
Arch Dermatol 98, 273-276
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The Chronology of Primary Herpes Simplex Infection of the Eye and Adnexal Glands.
D. Pavan-Langston and A. B. Nesburn (1968)
Arch Ophthalmol 80, 258-264
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Recurrent Herpes Simplex Conjunctivitis.
D. C. Brown, A. B. Nesburn, J. S. Nauheim, D. Pavan-Langston, and H. E. Kaufman (1968)
Arch Ophthalmol 79, 733-735
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The Uvea.
S. B. Aronson (1968)
Arch Ophthalmol 79, 490-501
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Myxovirus-Like Structures in a Case of Human Chronic Polymyositis.
S.-m. Chou (1967)
Science 158, 1453-1455
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