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Science 23 June 1967:
Vol. 156. no. 3782, pp. 1628 - 1629
DOI: 10.1126/science.156.3782.1628
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Articles

Recurrent Herpes in the Rabbit and Man

Herbert E. Kaufman 1, David C. Brown 1, and Emily Maloney Ellison 1

1 Department of Ophthalmology, University of Florida, Gainesville 32601

Herpesvirus was present in secretory glands and frequently in tears of rabbits with recurrent herpetic keratitis even in the absence of corneal lesions. In normal people, herpesvirus could be cultured from saliva and tears. Chronic virus multiplication in structures such as the lacrimal and salivary glands, rather than latency, may cause recurrent herpetic disease.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Effect of Prophylactic Valacyclovir on the Presence of Human Herpesvirus DNA in Saliva of Healthy Individuals after Dental Treatment.
C. S. Miller, S. A. Avdiushko, R. J. Kryscio, R. J. Danaher, and R. J. Jacob (2005)
J. Clin. Microbiol. 43, 2173-2180
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HSV-1 DNA in Tears and Saliva of Normal Adults.
H. E. Kaufman, A. M. Azcuy, E. D. Varnell, G. D. Sloop, H. W. Thompson, and J. M. Hill (2005)
Invest. Ophthalmol. Vis. Sci. 46, 241-247
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Salivary Defense Factors in Herpes Simplex Virus Infection.
H. Valimaa, M. Waris, V. Hukkanen, M.F.J. Blankenvoorde, A.V. Nieuw Amerongen, and J. Tenovuo (2002)
Journal of Dental Research 81, 416-421
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Antigens of Herpes Simplex Virus in Whole Corneal Epithelial Sheets From Mice.
C. Shimeld, S. J. Lewkowicz-Moss, K. M. Lipworth, T. J. Hill, W. A. Blyth, and D. L. Easty (1986)
Arch Ophthalmol 104, 1830-1834
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Visceral Herpesvirus Infections in Leukemic Patients Receiving Cytarabine.
D. H. Buss, M. Scharyj, and D. R. White (1980)
JAMA 243, 1903-1905
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Herpesvirus in Sensory and Autonomic Ganglia After Eye Infection: Absence of Chronic Viral Shedding.
R. G. Martin, C. R. Dawson, P. Jones, B. Togni, C. Lyons, and J. O. Oh (1977)
Arch Ophthalmol 95, 2053-2056
   Abstract »    PDF »
Treatment of Labial Herpes.
G. R. Nugent and S. M. Chou (1973)
JAMA 224, 132
   Abstract »    PDF »
Idoxuridine in Herpes Simplex Virus (Type 1) Encephalitis: Experience with 29 Cases in Michigan, 1966 to 1971.
D. C. NOLAN, C. B. LAUTER, and A. M. LERNER (1973)
Ann Intern Med 78, 243-246
   Abstract »    PDF »
Latent Herpes Simplex Virus: Isolation From Rabbit Trigeminal Ganglia Between Episodes of Recurrent Ocular Infection.
A. B. Nesburn, M. L. Cook, and J. G. Stevens (1972)
Arch Ophthalmol 88, 412-417
   Abstract »    PDF »
Penetrating Grafts Using Herpes Convalescent Cornea.
R. W. Darrell (1972)
Arch Ophthalmol 87, 411-416
   Abstract »    PDF »
Cornea and Sclera.
P. R. Laibson (1970)
Arch Ophthalmol 83, 637-657
   PDF »
Broadening Spectrum of Herpesvirus hominis (Herpes Simplex).
(1970)
Arch Dermatol 101, 364-366
   PDF »
Chronic Herpes Simplex Infection of the Ocular Adnexa: Persistence of Virus in the Rabbit After Enucleation.
D. C. Brown and H. E. Kaufman (1969)
Arch Ophthalmol 81, 837-839
   Abstract »    PDF »
Disseminated Herpes Simplex in a Newborn: A Consequence of Infection in the Mother.
A. W. Hudson and C. McFarland (1969)
JAMA 208, 859-861
   Abstract »    PDF »
Herpes Simplex Virus in Mice: Electron Microscopy of Neural Spread.
E. R. Rabin, A. B. Jenson, and J. L. Melnick (1968)
Science 162, 126-127
   Abstract »    PDF »
Recurrent Herpes Simplex of the Hard Palate: Case Report and Comment Concerning Reinfection and Rarity of Disease in the Mouth.
S. A. Muller (1968)
Arch Dermatol 98, 273-276
   Abstract »    PDF »
The Chronology of Primary Herpes Simplex Infection of the Eye and Adnexal Glands.
D. Pavan-Langston and A. B. Nesburn (1968)
Arch Ophthalmol 80, 258-264
   Abstract »    PDF »
Recurrent Herpes Simplex Conjunctivitis.
D. C. Brown, A. B. Nesburn, J. S. Nauheim, D. Pavan-Langston, and H. E. Kaufman (1968)
Arch Ophthalmol 79, 733-735
   Abstract »    PDF »
The Uvea.
S. B. Aronson (1968)
Arch Ophthalmol 79, 490-501
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Myxovirus-Like Structures in a Case of Human Chronic Polymyositis.
S.-m. Chou (1967)
Science 158, 1453-1455
   Abstract »    PDF »


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Science. ISSN 0036-8075 (print), 1095-9203 (online)