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Science 23 June 1967:
Vol. 156. no. 3782, pp. 1609 - 1610
DOI: 10.1126/science.156.3782.1609
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Articles

Carboxy-Terminal Amino Acids of gammaA and gammaM Heavy Chains

Carlos A. Abel 1 and Howard M. Grey 1

1 Division of Experimental Pathology, Scripps Clinic and Research Foundation, La Jolla, California

The carboxy-terminal amino acids of alpha-and µ-chains from human immunoglobulins and alpha-chains from mouse immunoglobulins have been determined by carboxypeptidase digestion and hydrazinolysis. The data suggest the following carboxy-terminal sequences: human µ: Ala-Gly-Thr-Cys-TyrCOOH; human alpha: Thr-Cys-TyrCOOH; murine alpha: (Ileu, Cys)-TyrCOOH.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Immunoglobulin Structure: Variability and Homology.
F. W. Putnam (1969)
Science 163, 633-643
   PDF »
Macroglobulin Structure: Homology of Mu and Gamma Heavy Chains of Human Immunoglobulins.
M. Wikler, H. Kohler, T. Shinoda, and F. W. Putnam (1969)
Science 163, 75-78
   Abstract »    PDF »


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Science. ISSN 0036-8075 (print), 1095-9203 (online)