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Science 16 June 1967:
Vol. 156. no. 3781, pp. 1508 - 1510
DOI: 10.1126/science.156.3781.1508
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Articles

Intrauterine Devices: Effects on Ulrastructure of Human Endometrium

Ralph M. Wynn 1

1 Department of Obstetrics and Gynecology, State University of New York, Downstate Medical Center, Brooklyn 11203

The human endometrium, studied with the electron microscope, undergoes asynchronous and premature cyclic development in response to inin uterine contraceptive devices. Typical nucleolar channel systems and other cellular characteristics of the normal secretory phase appear before ovulation, and decidualization occurs several days prematurely. Disturbance of the synchrony of ovular and endometrial development may be a mechanism of contraceptive action of these devices.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Nuclear pore complex proteins mark the implantation window in human endometrium.
E. Guffanti, N. Kittur, Z. N. Brodt, A. J. Polotsky, S. M. Kuokkanen, D. S. Heller, S. L. Young, N. Santoro, and U. T. Meier (2008)
J. Cell Sci. 121, 2037-2045
   Abstract »    Full Text »    PDF »
The Nucleolar Channel System of Human Endometrium Is Related to Endoplasmic Reticulum and R-Rings.
N. Kittur, G. Zapantis, M. Aubuchon, N. Santoro, D. P. Bazett-Jones, and U. T. Meier (2007)
Mol. Biol. Cell 18, 2296-2304
   Abstract »    Full Text »    PDF »
Intranuclear endoplasmic reticulum induced by Nopp140 mimics the nucleolar channel system of human endometrium.
C. Isaac, J. W. Pollard, and U. T. Meier (2001)
J. Cell Sci. 114, 4253-4264
   Abstract »    Full Text »    PDF »
Intrauterine Devices: Contraceptive or Abortifacient?.
W. A. Krotoski and R. M. Wynn (1967)
Science 157, 1465
   PDF »


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