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Science 28 April 1967:
Vol. 156. no. 3774, pp. 521 - 522
DOI: 10.1126/science.156.3774.521
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Articles

Human Polymorphonuclear Leukocytes: Demonstration of Microtubules and Effect of Colchicine

Stephen E. Malawista 1 and Klaus G. Bensch 1

1 Department of Internal Medicine and Pathology, Yale University School of Medicine, New Haven, Connecticut

Microtubules are demonstrable in mature human polymorphonuclear leukocytes, even after prolonged incubation in vitro. These organelles are not seen after treatment with colchicine, which has various functional effects on these cells but does not inhibit phagocytosis.


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Science. ISSN 0036-8075 (print), 1095-9203 (online)