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Science 24 March 1967:
Vol. 155. no. 3769, pp. 1543 - 1545
DOI: 10.1126/science.155.3769.1543
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Articles

Virus-Like Particles in Established Murine Cell Lines: Electron-Microscopic Observations

David A. Kindig 1 and W. H. Kirsten 1

1 Departments of Pathology and Pediatrics, University of Chicago, Chicago, Illinois

Virus-like particles identical in morphology to the RNA tumor vi ruses have been observed by electron microscopy in six lines of murine L cells and one line of murine liver cells. Control cultures of embryonic mouse cells and 3T3 cells do not contain the particles, and no biologic activity has as yet been associated with them.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Porcine endogenous retroviruses: in vitro host range and attempts to establish small animal models.
V. Specke, S. J. Tacke, K. Boller, J. Schwendemann, and J. Denner (2001)
J. Gen. Virol. 82, 837-844
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Mammalian Cells in Culture Frequently Release Type C Viruses.
M. M. Lieber, R. E. Benveniste, D. M. Livingston, and G. J. Todaro (1973)
Science 182, 56-59
   Abstract »    PDF »
Induction of Murine C-Type Viruses from Clonal Lines of Virus-Free BaALB/3T3 Cells.
S. A. Aaronson, G. J. Todaro, and E. M. Scolnick (1971)
Science 174, 157-159
   Abstract »    PDF »
Basis for the Acquaisition of Malignant Potential by Mouse Cells Cultivated in vitro.
S. A. Aaronson and G. J. Todaro (1968)
Science 162, 1024-1026
   Abstract »    PDF »


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Science. ISSN 0036-8075 (print), 1095-9203 (online)