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Science 10 March 1967:
Vol. 155. no. 3767, pp. 1288 - 1289
DOI: 10.1126/science.155.3767.1288

Articles

Oxidative Phosphorylation in Experimental Bilirubin Encephalopathy

Ivan Diamond 1 and Rudi Schmid 2

1 Section of Neurology, University of Chicago, Chicago, Illinois 60637
2 Department of Medicine, University of California School of Medicine, San Francisco 94122

Mitochondria from the whole brain or cerebellum of newborn guinea pigs with experimental bilirubin encephalopathy failed to exhibit uncoupling of oxidative phosphorylation. The pigment concentrations required to initiate uncoupling in vitro are much higher than those found in the brain of neurotoxic animals.


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Neonatal Jaundice.
A. Amanullah (1976)
Arch Pediatr Adolesc Med 130, 1274-1280
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Neonatal Hyperbilirubinemia and Kernicterus: Experimental Support for Treatment by Exposure to Visible Light.
I. Diamond and R. Schmid (1968)
Arch Neurol 18, 699-702
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Science. ISSN 0036-8075 (print), 1095-9203 (online)