Antibodies to Rabbit Cytochrome c Arising in Rabbits
Alfred Nisonoff 1,
Emanuel Margoliash 2, and
Morris Reichlin 3
1 Department of Microbiology, University of Illinois, College of Medicine, Chicago
2 Biochemical Research Department, Abbott Laboratories, North Chicago, Illinois
3 Department of Medicine, State University of New York at Buffalo
Antibodies reactive with rabbit cytochrome c have been observed in rabbits immunized with several heterologous cytochromes. Such antibodies have also been observed in rabbits immunized with rabbit cytochrome c conjugated to bovine gamma globulin. The serum of a rabbit immunized with human cyto chrome c reacted with the cytochrome c of the same rabbit.