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Science 16 December 1966:
Vol. 154. no. 3755, pp. 1464 - 1467
DOI: 10.1126/science.154.3755.1464
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Articles

Perineural Epithelium: A New Concept of its Role in the Integrity of the Peripheral Nervous System

T. R. Shanthaveerappa 1 and Geoffrey H. Bourne 1

1 Yerkes Regional Primate Research Center, Emory University, Atlanta,Georgia 30322

A multilayered, squamous-celled epithelial cell membrane covering the individual nerve fasciculi of the entire peripheral nervous system ( both voluntary and autonomic) including the sensory and motor end organs has been demonstrated in various species of animals, including man. This membrane is the direct continuation of the pia-arachnoid mater from the central nervous system.Functional significance of this membrane, especially as a diffusion barrier and as a protector of the peripheral nervous system, is briefly discussed.


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