Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Site Tools

  • AAAS
  • Subscribe
  • Feedback

Site Search

Search Advanced

Science 2 December 1966:
Vol. 154. no. 3753, pp. 1183 - 1185
DOI: 10.1126/science.154.3753.1183
Prev | Table of Contents | Next

Articles

Periventricular Cerebral Impedance after Intraventricular Injection of Calcium

H. H. Wang 1, T. J. Tarby 1, R. T. Kado 1, and W. R. Adey 1

1 Brain Research Institute, University of California, Los Angeles 90024

Injection of small volumes of calcium solution into the lateral ventricle of the cat wa followed by large electrical-impedance changes in gray matter bounding the ventricle, including the caudate nucleus and hippocampus. These changes lasted more than 24 hours and were accompanied by epileptiform electroencephalographic activity. Biweekly injections led to status epilepticus. Injections of similar amounts of magnesium ions were without comparable effects. Possible interactions between calcium ions and intercellular macromolecular material are discussed as a basis for certain impedance shifts in cerebral tissue.

To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)