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Science 4 November 1966:
Vol. 154. no. 3749, pp. 651 - 652
DOI: 10.1126/science.154.3749.651
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Articles

Homoreactant: A Naturally Occurring Autoantibody in Rabbits

William J. Mandy 1 and Lucy C. Kormeier 1

1 Department of Microbiology, University of Texas, Austin

Homoreactant, a factor found in the serum of every normal rabbit tested thus far, reacts specifically with buried antigenic determinants on the Fab-fragment of papain-digested autologous and homologous gammaG-globulin. It appears that rabbits normally produce naturally occurring autoantibodies.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)