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Science 30 September 1966:
Vol. 153. no. 3744, pp. 1657 - 1658
DOI: 10.1126/science.153.3744.1657
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Articles

Spontaneous Mammary Tumors: Decrease of Incidence in Mice Infected with an Enzyme-Elevafing Virus

Vernon Riley 1

1 Sloan-Kettering Institute for Cancer Research, Rye, New York

Mice infected with a virus which causes increased activity of lactate dehydrogenase, and of other enzymes in blood plasma, had a significantly lower incidence of spontaneous mammary carcinoma than did controls. When the experiment was terminated at 18 months, the incidence of mammary tumors in controls was 90 percent, and in infected mice, 53 percent.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
The LDH virus: an interfering biological contaminant.
V Riley, D. Spackman, G. Santisteban, G Dalldorf, I Hellstrom, K. Hellstrom, E. Lance, K. Rowson, B. Mahy, P Alexander, et al. (1978)
Science 200, 124-126
   PDF »
Mouse mammary tumors: alteration of incidence as apparent function of stress.
V Riley (1975)
Science 189, 465-467
   Abstract »    PDF »


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Science. ISSN 0036-8075 (print), 1095-9203 (online)