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Science 12 August 1966:
Vol. 153. no. 3737, pp. 749 - 751
DOI: 10.1126/science.153.3737.749

Articles

Continuity of Protein Synthesis Through Cleavage Metaphase

P. R. Gross 1 and B. J. Fry 1

1 Department of Biology, Massachusetts Institute of Technology, Cambridge

Protein synthesis continues without a decline in rate throughout the period of chromosome condensation and of cytokinesis in the first two cleavages of sea urchin embryos. The natural synchrony of the egg populations and the conditions of measurement allowed even a partial inhibition of synthesis to be observed. Our results do not explain the mechanism of inhibition of protein synthesis that occurs at metaphase in cultured mammalian cells, but it shows that such a change in rate is neither universal nor obligatory.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Protein Synthesis during First Cleavage of Sea Urchin Embryos.
H. Timourian (1966)
Science 154, 1055
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Science. ISSN 0036-8075 (print), 1095-9203 (online)