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Science 5 August 1966:
Vol. 153. no. 3736, pp. 641 - 643
DOI: 10.1126/science.153.3736.641
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Articles

Immunoglobulin M Allotypes of the Rabbit: Identification of a Second Specificity

Stewart Sell 1

1 Department of Pathology, University of Pittsburgh, School of Medicine, Pittsburgh, Pennsylvania 15213

Rabbit antiserums, originally prepared to react specifically with rabbit immunoglobulin allotypes Ab5 and Ab6, also react with some normal rabbit serums that clearly do not contain Ab5 or Ab6 allotypes. This reaction is due to antigenic specificity present on rabbit immunoglobulin M(IgM) and not on rabbit immunoglobulin G.Serums that contain this IgM allotype do not react with an antiserum that reacts with the known rabbit IgM allotype, Ms1. This specificity may therefore be identified as a second rabbit IgM allotype, Ms2.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Restrictions on Antibody Production by Single Cells.
P. G. H. Gell (1967)
Cold Spring Harb Symp Quant Biol 32, 441-445
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Science. ISSN 0036-8075 (print), 1095-9203 (online)