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Science 15 July 1966:
Vol. 153. no. 3733, pp. 303 - 305
DOI: 10.1126/science.153.3733.303
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Articles

Rat Mammary Gland RNA: Incorporation of C14-Formate and Effect of Hormones and 7,12-Dimethylbenz[alanthracene

Paul R. Libby 1 and Thomas L. Dao 1

1 Department of Breast Surgery, Roswell Park Memorial Institute, Buffalo, New York

In female rats, the incorporation of sodium C14-formate into mammary gland RNA decreases immediately after a singlefeeding of 20 milligrams of 7,12-dimethylbenz[a] anthracene. In males, there is a gradual increase in the incorporation. In castrated rats, the decrease or increase of C14-formate incorporation is dependent on the presence of estrogen or androgen, respectively.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)