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Science 8 July 1966:
Vol. 153. no. 3732, pp. 180 - 182
DOI: 10.1126/science.153.3732.180
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Articles

Beta-1C-Globulin: Metabolism in Glomerulonephritis

Chester A. Alper 1, Alan S. Levin 1, and Fred S. Rosen 1

1 Department of Medicine, Children's Hospital Medical Center, Boston, Massachusetts 02115

The metabolism of beta1C-globulin labeled with iodine-131 was studied in six normal individuals and in three individuals with glomerulonephritis who exhibited markedly reduced serum concentrations of this protein. Fractional of serum beta1C-globulin in glomerulonephritis appears to be chiefly secondary to decreased synthesis.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Hypocomplementemic (Membranoproliferative) Glomerulonephritis: Immunosuppressive Therapy.
N. H. Holland and N. M. Bennett (1972)
Arch Pediatr Adolesc Med 123, 439-445
   Abstract »    PDF »
Human C'3: Evidence for the Liver as the Primary Site of Synthesis.
C. A. Alper, A. M. Johnson, A. G. Birtch, and F. D. Moore (1969)
Science 163, 286-288
   Abstract »    PDF »
Acute Glomerulonephritis Associated With Normal Serum B1C-Globulin.
L. U. Tina, J. B. D'Albora, T. T. Antonovych, J. A. Bellanti, and P. L. Calcagno (1968)
Arch Pediatr Adolesc Med 115, 29-36
   Abstract »    PDF »
Complement Research: Fundamental and Applied.
H. J. Rapp and T. Borsos (1966)
JAMA 198, 1347-1354
   Abstract »    PDF »


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Science. ISSN 0036-8075 (print), 1095-9203 (online)