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Science 1 July 1966:
Vol. 153. no. 3731, pp. 80 - 82
DOI: 10.1126/science.153.3731.80
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Articles

Mechanism of a Reaction in Vitro Associated with Delayed-Type Hypersensitivity

Barry R. Bloom 1 and Boyce Bennett 2

1 Department of Microbiology and Immunology and Department of Pathology, Albert Einstein College of Medicine, New York 10461
2 Departmnent of Microbiology and Immunology and Department of Pathology, Albert Einstein College of Medicine, New York 10461

The cell type responsible for inhibition by antigen of migration in vitro of peritoneal exudate cells obtained from tuberculin-hypersensitive guinea pigs was studied. Exudate populations were separated into component cell types, the lymphocyte and the macrophage. Peritoneal lymphocytes from sensitive donors were the immunologically active cells in this system, the macrophages, being merely indicator cells which migrate. Sensitized peritoneal lymphocyte populations, upon interaction with specific antigen in vitro, elaborated into the medium a soluble material capable of inhibiting migration of normal exudate cells.


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Oxygen regulation of macrophage migration inhibitory factor in human placenta.
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Am J Physiol Endocrinol Metab 292, E272-E280
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Reproductive Sciences 13, 263-270
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Macrophage Migration Inhibitory Factor Increases Neuronal Delayed Rectifier K+ Current.
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J Neurophysiol 95, 1042-1048
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Human decidual natural killer cells as a source and target of macrophage migration inhibitory factor.
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Immunosuppressive Factors Secreted by Human Amniotic Epithelial Cells.
H. Li, J. Y. Niederkorn, S. Neelam, E. Mayhew, R. A. Word, J. P. McCulley, and H. Alizadeh (2005)
Invest. Ophthalmol. Vis. Sci. 46, 900-907
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Macrophage Migration Inhibitory Factor Promotes Tumor Invasion and Metastasis via the Rho-Dependent Pathway.
B. Sun, J. Nishihira, T. Yoshiki, M. Kondo, Y. Sato, F. Sasaki, and S. Todo (2005)
Clin. Cancer Res. 11, 1050-1058
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Macrophage Migration Inhibitory Factor Is Released from Pituitary Folliculo-Stellate-Like Cells by Endotoxin and Dexamethasone and Attenuates the Steroid-Induced Inhibition of Interleukin 6 Release.
T. Tierney, R. Patel, C. A. S. Stead, L. Leng, R. Bucala, and J. C. Buckingham (2005)
Endocrinology 146, 35-43
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Limited Capability of Regional Lymph Nodes to Eradicate Metastatic Cancer Cells.
H. Nagata, T. Arai, Y. Soejima, H. Suzuki, H. Ishii, and T. Hibi (2004)
Cancer Res. 64, 8239-8248
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Mechanisms regulating the recruitment of macrophages into hypoxic areas of tumors and other ischemic tissues.
C. Murdoch, A. Giannoudis, and C. E. Lewis (2004)
Blood 104, 2224-2234
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Pathogenesis of Malaria and Clinically Similar Conditions.
I. A. Clark, L. M. Alleva, A. C. Mills, and W. B. Cowden (2004)
Clin. Microbiol. Rev. 17, 509-539
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Macrophage Migration Inhibitory Factor Deficiency Impairs Atherosclerosis in Low-Density Lipoprotein Receptor-Deficient Mice.
J.-H. Pan, G. K. Sukhova, J.-T. Yang, B. Wang, T. Xie, H. Fu, Y. Zhang, A. R. Satoskar, J. R. David, C. N. Metz, et al. (2004)
Circulation 109, 3149-3153
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Xenopus laevis Macrophage Migration Inhibitory Factor Is Essential for Axis Formation and Neural Development.
M. Suzuki, Y. Takamura, M. Maeno, S. Tochinai, D. Iyaguchi, I. Tanaka, J. Nishihira, and T. Ishibashi (2004)
J. Biol. Chem. 279, 21406-21414
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Macrophage Migration Inhibitory Factor Is Induced by Thrombin and Factor Xa in Endothelial Cells.
T. Shimizu, J. Nishihira, H. Watanabe, R. Abe, A. Honda, T. Ishibashi, and H. Shimizu (2004)
J. Biol. Chem. 279, 13729-13737
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Role of Macrophage Migration Inhibitory Factor in Conjunctival Pathology in Ocular Cicatricial Pemphigoid.
M. S. Razzaque, C. S. Foster, and A. R. Ahmed (2004)
Invest. Ophthalmol. Vis. Sci. 45, 1174-1181
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Ultraviolet A-induced Production of Matrix Metalloproteinase-1 Is Mediated by Macrophage Migration Inhibitory Factor (MIF) in Human Dermal Fibroblasts.
H. Watanabe, T. Shimizu, J. Nishihira, R. Abe, T. Nakayama, M. Taniguchi, H. Sabe, T. Ishibashi, and H. Shimizu (2004)
J. Biol. Chem. 279, 1676-1683
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Macrophage migration inhibitory factor delays apoptosis in neutrophils by inhibiting the mitochondria-dependent death pathway.
R. BAUMANN, C. CASAULTA, D. SIMON, S. CONUS, S. YOUSEFI, and H.-U. SIMON (2003)
FASEB J 17, 2221-2230
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Aldose Reductase and Macrophage Migration Inhibitory Factor Are Associated with Epididymosomes and Spermatozoa in the Bovine Epididymis.
G. Frenette, C. Lessard, E. Madore, M. A. Fortier, and R. Sullivan (2003)
Biol Reprod 69, 1586-1592
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Interferon-{tau} Stimulates Secretion of Macrophage Migration Inhibitory Factor from Bovine Endometrial Epithelial Cells.
B. Wang and A. K. Goff (2003)
Biol Reprod 69, 1690-1696
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MIF Signal Transduction Initiated by Binding to CD74.
L. Leng, C. N. Metz, Y. Fang, J. Xu, S. Donnelly, J. Baugh, T. Delohery, Y. Chen, R. A. Mitchell, and R. Bucala (2003)
J. Exp. Med. 197, 1467-1476
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Expression of Macrophage Migration Inhibitory Factor in Acute Ischemic Myocardial Injury.
C.-M. Yu, K. W.-H. Lai, Y.-X. Chen, X.-R. Huang, and H. Y. Lan (2003)
J. Histochem. Cytochem. 51, 625-631
   Abstract »    Full Text »    PDF »
Expression of macrophage migration inhibitory factor in diffuse systemic sclerosis.
E Selvi, S A Tripodi, M Catenaccio, S Lorenzini, D Chindamo, S Manganelli, R Romagnoli, F Ietta, L Paulesu, C Miracco, et al. (2003)
Ann Rheum Dis 62, 460-464
   Abstract »    Full Text »    PDF »
The Apa Protein of Mycobacterium tuberculosis Stimulates Gamma Interferon-Secreting CD4+ and CD8+ T Cells from Purified Protein Derivative-Positive Individuals and Affords Protection in a Guinea Pig Model.
P. Kumar, R. R. Amara, V. K. Challu, V. K. Chadda, and V. Satchidanandam (2003)
Infect. Immun. 71, 1929-1937
   Abstract »    Full Text »
Macrophage migration inhibitory factor (MIF) regulates host responses to endotoxin through modulation of Toll-like receptor 4 (TLR4).
T. Roger, C. Froidevaux, C. Martin, and T. Calandra (2003)
Innate Immunity 9, 119-123
   Abstract »    PDF »
Macrophage Migration Inhibitory Factor Deficiency Is Associated with Altered Cell Growth and Reduced Susceptibility to Ras-mediated Transformation.
O. Petrenko, G. Fingerle-Rowson, T. Peng, R. A. Mitchell, and C. N. Metz (2003)
J. Biol. Chem. 278, 11078-11085
   Abstract »    Full Text »    PDF »
Macrophage Migration Inhibitory Factor and CXC Chemokine Expression in Non-Small Cell Lung Cancer: Role in Angiogenesis and Prognosis.
E. S. White, K. R. Flaherty, S. Carskadon, A. Brant, M. D. Iannettoni, J. Yee, M. B. Orringer, and D. A. Arenberg (2003)
Clin. Cancer Res. 9, 853-860
   Abstract »    Full Text »    PDF »
In Vivo Blockade of Macrophage Migration Inhibitory Factor Ameliorates Acute Experimental Autoimmune Encephalomyelitis by Impairing the Homing of Encephalitogenic T Cells to the Central Nervous System.
C. M. Denkinger, M. Denkinger, J. J. Kort, C. Metz, and T. G. Forsthuber (2003)
J. Immunol. 170, 1274-1282
   Abstract »    Full Text »    PDF »
Quantification of Macrophage Migration Inhibitory Factor mRNA Expression in Non-Small Cell Lung Cancer Tissues and Its Clinical Significance.
M. Tomiyasu, I. Yoshino, R. Suemitsu, T. Okamoto, and K. Sugimachi (2002)
Clin. Cancer Res. 8, 3755-3760
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Homologues of Human Macrophage Migration Inhibitory Factor from a Parasitic Nematode. GENE CLONING, PROTEIN ACTIVITY, AND CRYSTAL STRUCTURE.
X. Zang, P. Taylor, J. M. Wang, D. J. Meyer, A. L. Scott, M. D. Walkinshaw, and R. M. Maizels (2002)
J. Biol. Chem. 277, 44261-44267
   Abstract »    Full Text »    PDF »
Macrophage migration inhibitory factor (MIF) plays a pivotal role in immunity against Salmonella typhimurium.
H. Koebernick, L. Grode, J. R. David, W. Rohde, M. S. Rolph, H.-W. Mittrucker, and S. H. E. Kaufmann (2002)
PNAS 99, 13681-13686
   Abstract »    Full Text »    PDF »
Release of Macrophage Migration Inhibitory Factor and CXCL8/Interleukin-8 from Lung Epithelial Cells Rendered Necrotic by Influenza A Virus Infection.
U. Arndt, G. Wennemuth, P. Barth, M. Nain, Y. Al-Abed, A. Meinhardt, D. Gemsa, and M. Bacher (2002)
J. Virol. 76, 9298-9306
   Abstract »    Full Text »    PDF »
The Presence of Macrophage Migration Inhibitory Factor in Human Trabecular Meshwork and its Upregulatory Effects on the T Helper 1 Cytokine.
H. Takase, S. Sugita, D. J. Rhee, Y. Imai, C. Taguchi, Y. Sugamoto, Y. Tagawa, J. Nishihira, P. Russell, and M. Mochizuki (2002)
Invest. Ophthalmol. Vis. Sci. 43, 2691-2696
   Abstract »    Full Text »    PDF »
Accumulation of the mitochondrial form of the sulphydryl oxidase Erv1p/Alrp during the early stages of spermatogenesis.
M. Klissenbauer, S. Winters, U. A. O. Heinlein, and T. Lisowsky (2002)
J. Exp. Biol. 205, 1979-1986
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Contribution of Macrophage Migration Inhibitory Factor to Extracellular Signal-regulated Kinase Activation by Oxidative Stress in Cardiomyocytes.
J. Fukuzawa, J. Nishihira, N. Hasebe, T. Haneda, J. Osaki, T. Saito, T. Nomura, T. Fujino, N. Wakamiya, and K. Kikuchi (2002)
J. Biol. Chem. 277, 24889-24895
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The Tautomerase Active Site of Macrophage Migration Inhibitory Factor Is a Potential Target for Discovery of Novel Anti-inflammatory Agents.
J. B. Lubetsky, A. Dios, J. Han, B. Aljabari, B. Ruzsicska, R. Mitchell, E. Lolis, and Y. Al-Abed (2002)
J. Biol. Chem. 277, 24976-24982
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Role of macrophage migration inhibitory factor in bleomycin-induced lung injury and fibrosis in mice.
Y. Tanino, H. Makita, K. Miyamoto, T. Betsuyaku, Y. Ohtsuka, J. Nishihira, and M. Nishimura (2002)
Am J Physiol Lung Cell Mol Physiol 283, L156-L162
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Macrophage Migration Inhibitory Factor Up-regulates Matrix Metalloproteinase-9 and -13 in Rat Osteoblasts. RELEVANCE TO INTRACELLULAR SIGNALING PATHWAYS.
S. Onodera, J. Nishihira, K. Iwabuchi, Y. Koyama, K. Yoshida, S. Tanaka, and A. Minami (2002)
J. Biol. Chem. 277, 7865-7874
   Abstract »    Full Text »    PDF »
Macrophage Migration Inhibitory Factor Is Markedly Expressed in Active and Early-Stage Endometriotic Lesions.
R. Kats, C. N. Metz, and A. Akoum (2002)
J. Clin. Endocrinol. Metab. 87, 883-889
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Macrophage migration inhibitory factor (MIF) modulates innate immune responses induced by endotoxin and Gram-negative bacteria.
T. Roger, M. P. Glauser, and T. Calandra (2001)
Innate Immunity 7, 456-460
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Macrophage migration inhibitory factor as a redox-sensitive cytokine in cardiac myocytes.
M. Takahashi, J. Nishihira, M. Shimpo, Y. Mizue, S. Ueno, H. Mano, E. Kobayashi, U. Ikeda, and K. Shimada (2001)
Cardiovasc Res 52, 438-445
   Abstract »    Full Text »    PDF »
Novel Role of Macrophage Migration Inhibitory Factor in Angiotensin II Regulation of Neuromodulation in Rat Brain.
S. Busche, S. Gallinat, M. A. Fleegal, M. K. Raizada, and C. Sumners (2001)
Endocrinology 142, 4623-4630
   Abstract »    Full Text »    PDF »
Macrophage Migration Inhibitory Factor in the Human Endometrium: Expression and Localization During the Menstrual Cycle and Early Pregnancy.
F. Arcuri, C. Ricci, F. Ietta, M. Cintorino, S. A. Tripodi, I. Cetin, E. Garzia, F. Schatz, P. Klemi, R. Santopietro, et al. (2001)
Biol Reprod 64, 1200-1205
   Abstract »    Full Text »
De Novo Expression of Macrophage Migration Inhibitory Factor in Atherogenesis in Rabbits.
S.-G. Lin, X.-Y. Yu, Y.-X. Chen, X. R. Huang, C. Metz, R. Bucala, C.-P. Lau, and H. Y. Lan (2000)
Circ. Res. 87, 1202-1208
   Abstract »    Full Text »    PDF »
Identification of Macrophage Migration Inhibitory Factor as a Potent Endothelial Cell Growth-Promoting Agent Released by Ectopic Human Endometrial Cells.
Y. Yang, P. Degranpré, A. Kharfi, and A. Akoum (2000)
J. Clin. Endocrinol. Metab. 85, 4721-4727
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Increase of macrophage migration inhibitory factor in sera of patients with iridocyclitis.
N. Kitaichi, S. Kotake, Y. Mizue, H. Matsuda, K. Onoé, and J. Nishihira (2000)
Br. J. Ophthalmol. 84, 1423-1425
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Human Uveal Melanoma Cells Produce Macrophage Migration-Inhibitory Factor to Prevent Lysis by NK Cells.
A. C. Repp, E. S. Mayhew, S. Apte, and J. Y. Niederkorn (2000)
J. Immunol. 165, 710-715
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Macrophage Migration Inhibitory Factor-Induced Ca2+ Response in Rat Testicular Peritubular Cells.
G. Wennemuth, G. Aumüller, M. Bacher, and A. Meinhardt (2000)
Biol Reprod 62, 1632-1639
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Macrophage migration inhibitory factor levels in the vitreous of patients with proliferative diabetic retinopathy.
Y. Mitamura, S. Takeuchi, A. Matsuda, Y. Tagawa, Y. Mizue, and J. Nishihira (2000)
Br. J. Ophthalmol. 84, 636-639
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Macrophage Migration Inhibitory Factor in the Bovine Corpus Luteum: Characterization of Steady-State Messenger Ribonucleic Acid and Immunohistochemical Localization.
S. E. Bove, M. G. Petroff, M. Nishibori, and J. L. Pate (2000)
Biol Reprod 62, 879-885
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Macrophage Migration Inhibitory Factor Up-regulates Expression of Matrix Metalloproteinases in Synovial Fibroblasts of Rheumatoid Arthritis.
S. Onodera, K. Kaneda, Y. Mizue, Y. Koyama, M. Fujinaga, and J. Nishihira (2000)
J. Biol. Chem. 275, 444-450
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Expression of Macrophage Migration Inhibitory Factor Transcript and Protein by First-Trimester Human Trophoblasts.
F. Arcuri, M. Cintorino, R. Vatti, A. Carducci, S. Liberatori, and L. Paulesu (1999)
Biol Reprod 60, 1299-1303
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Enzyme Activity of Macrophage Migration Inhibitory Factor toward Oxidized Catecholamines.
J. Matsunaga, D. Sinha, L. Pannell, C. Santis, F. Solano, G. J. Wistow, and V. J. Hearing (1999)
J. Biol. Chem. 274, 3268-3271
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Induction of macrophage migration inhibitory factor in human ovary by human chorionic gonadotrophin.
S.-i. Wada, T. Kudo, M. Kudo, N. Sakuragi, H. Hareyama, J. Nishihira, and S. Fujimoto (1999)
Hum. Reprod. 14, 395-399
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Macrophage migration inhibitory factor is a critical mediator of the activation of immune cells by exotoxins of Gram-positive bacteria.
T. Calandra, L. A. Spiegel, C. N. Metz, and R. Bucala (1998)
PNAS 95, 11383-11388
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Migration Inhibitory Factor Induces Killing of Leishmania major by Macrophages: Dependence on Reactive Nitrogen Intermediates and Endogenous TNF-{alpha}.
S. Juttner, J. Bernhagen, C. N. Metz, M. Rollinghoff, R. Bucala, and A. Gessner (1998)
J. Immunol. 161, 2383-2390
   Abstract »    Full Text »    PDF »
Effect of Anti-Macrophage Migration Inhibitory Factor Antibody on Lipopolysaccharide-induced Pulmonary Neutrophil Accumulation.
H. MAKITA, M. NISHIMURA, K. MIYAMOTO, T. NAKANO, Y. TANINO, J. HIROKAWA, J. NISHIHIRA, and Y. KAWAKAMI (1998)
Am. J. Respir. Crit. Care Med. 158, 573-579
   Abstract »    Full Text »    PDF »
Cutting Edge: Role of Macrophage Migration Inhibitory Factor in Inhibiting NK Cell Activity and Preserving Immune Privilege.
R. S. Apte, D. Sinha, E. Mayhew, G. J. Wistow, and J. Y. Niederkorn (1998)
J. Immunol. 160, 5693-5696
   Abstract »    Full Text »    PDF »
Macrophage Migration Inhibitory Factor Interactions with Glutathione and S-Hexylglutathione.
M. D. Swope, H.-W. Sun, B. Klockow, P. Blake, and E. Lolis (1998)
J. Biol. Chem. 273, 14877-14884
   Abstract »    Full Text »    PDF »
Chemokines.
B. J. Rollins (1997)
Blood 90, 909-928
   Full Text »    PDF »
Insulin secretion is regulated by the glucose-dependent production of islet beta  cell macrophage migration inhibitory factor.
G. Waeber, T. Calandra, R. Roduit, J.-A. Haefliger, C. Bonny, N. Thompson, B. Thorens, E. Temler, A. Meinhardt, M. Bacher, et al. (1997)
PNAS 94, 4782-4787
   Abstract »    Full Text »    PDF »
The Pathogenic Role of Macrophage Migration Inhibitory Factor in Immunologically Induced Kidney Disease in the Rat.
H. Y. Lan, M. Bacher, N. Yang, W. Mu, D. J. Nikolic-Paterson, C. Metz, A. Meinhardt, R. Bucala, and R. C. Atkins (1997)
J. Exp. Med. 185, 1455-1466
   Abstract »    Full Text »    PDF »
Pituitary Cytokine and Growth Factor Expression and Action.
D. Ray and S. Melmed (1997)
Endocr. Rev. 18, 206-228
   Abstract »    Full Text »
Proton Magnetic Resonance Imaging and Spectroscopic Studies of the Pathogenesis and Treatment of Juvenile Dermatomyositis.
J.M. Slopis, E.F. Jackson, P.A. Narayana, S.C. Papasozomenos, and I.J. Butler (1993)
J Child Neurol 8, 242-249
   Abstract »    PDF »
Colony-Stimulating Factors and Host Defense.
R. H. Weisbart, J. C. Gasson, and D. W. Golde (1989)
Ann Intern Med 110, 297-303
   Abstract »    PDF »
Interferon-Gamma, the Activated Macrophage, and Host Defense Against Microbial Challenge.
H. W. MURRAY (1988)
Ann Intern Med 108, 595-608
   Abstract »    PDF »
Breast Milk Immunology: A Frontier in Infant Nutrition.
W. B. Pittard III (1979)
Arch Pediatr Adolesc Med 133, 83-87
   Abstract »    PDF »
Collagenase production by lymphokine-activated macrophages.
L. Wahl, S. Wahl, S. Mergenhagen, and G. Martin (1975)
Science 187, 261-263
   Abstract »    PDF »
Inhibition of Leukocyte Migration by Human Tumors: Effect on Patient Survival.
W. H. Wolberg (1974)
Arch Surg 109, 211-214
   Abstract »    PDF »
Modulation of Inflammation and Immunity by Cyclic AMP.
H. R. Bourne, Y. Weinstein, K. L. Melmon, L. M. Lichtenstein, C. S. Henney, and G. M. Shearer (1974)
Science 184, 19-28
   PDF »
Cell-Mediated Hypersensitivity to Neural Antigens: Occurrence in Human Patients and Nonhuman Primates With Neurological Diseases.
P. O. Behan, W. M. H. Behan, R. G. Feldman, and M. W. Kies (1972)
Arch Neurol 27, 145-152
   Abstract »    PDF »
Diseases of Cellular Immunity.
E. R. STIEHM, A. J. AMMANN, E. V. BARNETT, C. G. CRADDOCK, H. H. FUDENBERG, and G. J. LAWLOR JR. (1972)
Ann Intern Med 77, 101-116
   Abstract »    PDF »
Tumor hnmunity: Tumor Suppression in vivo Initiated by Soluble Products of Specifically Stimulated Lymphocytes.
I. D. Bernstein, D. E. Thor, B. Zbar, and H. J. Rapp (1971)
Science 172, 729-731
   Abstract »    PDF »
Production of Macrophage Inhibitory Factor by Patients With Leprosy.
S. I. Katz, B. H. DeBetz, and N. Zaias (1971)
Arch Dermatol 103, 358-361
   Abstract »    PDF »
Primary Lymphopenic Immunologic Deficiency: Disseminated Mycobacterium kansasii Infection.
G. H. McCracken Jr. and R. C. Reynolds (1970)
Arch Pediatr Adolesc Med 120, 143-147
   Abstract »    PDF »
Induction of Interferon by Nonviral Agents.
E. De Clercq and T. C. Merigan (1970)
Arch Intern Med 126, 94-108
   Abstract »    PDF »


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