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Science 10 June 1966:
Vol. 152. no. 3728, pp. 1520 - 1521
DOI: 10.1126/science.152.3728.1520
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Articles

Light-Chain Heterogeneity of Cold Agglutinins

Nicolas Costea 1, Vincent Yakulis 1, and Paul Heller 1

1 Veterans Adm2inistration, West Side Hospital, University of Illinois, Chicago 60612

Cold agglutinins with specificity to I or to i antigens of humanadult or cord-blood erythrocytes produced during the course of Mycoplasma pneumoniae infection and infectious mononucleosis contain light chains of K and L types. However, cold agglutinin isolated from the serums of patients with chronic cold-agglutinin hemolytic anemia contains only type K light chains. The experimental evidence suggests that some cold agglutinins contain both types of light chains in the same molecule.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Correlation of Abnormal Immunoglobulin With Clinical Features of Myeloma: A Cooperative Study by Acute Leukemia Group B.
(1975)
Arch Intern Med 135, 46-52
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