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Science 20 May 1966:
Vol. 152. no. 3725, pp. 1086 - 1087
DOI: 10.1126/science.152.3725.1086
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Articles

Glucocorticoid-Induced Resistance to Deoxycholate Lysis in HeLa Cells

George Melnykovych 1

1 U.S. Veterans Administration Hospital, Kansas City, Missouri, and Department of Microbiology, University of Kansas Medical School, Kansas City

HeLa cells exposed to low concentrations of prednisolone and other glucocorticoids acquired resistance to lysis with sodium deoxycholate. The effect showed considerable specificity by being confined to steroids that cause elevation of alkaline phosphatase in tissue culture and are known to have anti-inflammatory effects in vivo.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Psychomotor Activity and Serum Creatine Phosphokinase Activity.
F. G. Foster and D. J. Kupfer (1973)
Arch Gen Psychiatry 29, 752-758
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Sialic Acid in HeLa Cells: Effect of Hydrocortisone.
R. Carubelli and M. J. Griffin (1967)
Science 157, 693-694
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