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Science 6 May 1966:
Vol. 152. no. 3723, pp. 773 - 775
DOI: 10.1126/science.152.3723.773
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Articles

Immunochemical Characterization of Polyribonucleotides

Jacques Panijel 1, Claude Souleil 1, and Philippe Cayeux 1

1 Service des Streptocoques, Institut Pasteur, 25 rue du Docteur Roux, Paris 15e, France

The degree of organization of polyribonucleotides determines their modalities of reaction with antibodies (NG-I) which are present in serums of animals hyperimmunized with ribosomes. The immunochemical behavior of the highly helical two-stranded complex of polyadenylic acid and polyuridylic acid and the corresponding three-stranded complex of one molecule of polyadenylic acid and two molecules of polyuridylic acid can be determined from examination of the associatinge and nonassociating mixtures of polyadenylic and polyuridylic acids. The immunochemical characteristics of various forms of polyinosinic acid in solution are described.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)