Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Science 29 April 1966:
Vol. 152. no. 3722, pp. 657 - 659
DOI: 10.1126/science.152.3722.657
Prev | Table of Contents | Next

Articles

Metabolism of Alveolar Cells: Histochemical Evidence and Relation to Pulmonary Surfactant

Sami I. Said 1, Richard M. Klein 1, Laura W. Norrell 1, and Yvonne T. Maddox 1

1 Department of Medicine, Medical College of Virginia, Richmond 23219

Large alveolar cells of normal dog lung are rich in enzymes concerned with oxidative and synthetic pathways. In three experimental situations where ability of the lung to produce surfactant was impaired, the enzyme-rich cells were lacking or absent. Findings support the concept that these cells are sites of active metabolism, possibly including production of surfactant.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Alveolar Clearance of Aerosols.
P. E. Morrow (1973)
Arch Intern Med 131, 101-108
   Abstract »    PDF »
Beagle Dog Pulmonary Surfactant Lipids: Lipid Composition of Pulmonary Tissue, Exfoliated Lining Cells, and Surfactant.
R. C. Pfleger and H. G. Thomas (1971)
Arch Intern Med 127, 863-872
   Abstract »    PDF »
Properties of Alveolar Cells and Tissues That Strengthen Alveolar Defenses.
S. P. Sorokin (1970)
Arch Intern Med 126, 450-463
   Abstract »    PDF »
Blood Gas Determinations in the Severely Wounded in Hemorrhagic Shock.
B. D. Lowery, C. T. Cloutier, and L. C. Carey (1969)
Arch Surg 99, 330-338
   Abstract »    PDF »
Bronchiolar and Large Alveolar Cell in Pulmonary Phospholipid Metabolism.
A. H. Niden (1967)
Science 158, 1323-1324
   Abstract »    PDF »


To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)