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Science 15 April 1966:
Vol. 152. no. 3720, pp. 352 - 354
DOI: 10.1126/science.152.3720.352
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Articles

Glucose-6-Phosphatase in Tubular Endoplasmic Reticulum of Hepatocytes

Sidney I. Rosen 1, George W. Kelly 1, and Virginia B. Peters 1

1 Murray and Leonie Guggenheim Foundation, Institute for Dental Research, New York University, New York 10010

The histochemical localization of glucose-6-phosphatase activity in neonatal mouse liver was studied under electron microscopy. The activity was demonstrated in the tubular endoplasmic reticulum, which pervades the glycogen areas of the cell during glycogenolysis. Activity was also demonstrated in the nuclear envelope and ergastoplasm.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)