Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Science 18 March 1966:
Vol. 151. no. 3716, pp. 1395 - 1397
DOI: 10.1126/science.151.3716.1395
Prev | Table of Contents | Next

Articles

Immunological Competence: Alteration by Whole Body X-Irradiation and Shielding of Selected Lymphoid Tissues

Joshua Miller 1

1 Yale University School of Medicine, New Haven, Connecticut

The spleen and thymus of 6-week-old mice contain similar numbers of lymphoid cells. A lethal dose of x-irradiation given to animials whose thymus, midgut, or hindlimbs were shielded at the same time resulted in permanent acceptance of allografts, while a similar dose given to spleen-shielded mice so irradiated resulted in a normal rejection pattern. The return of immunological competence was related to the state of the lymphoid organs with different types of shielding.

To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)