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Science 4 March 1966:
Vol. 151. no. 3714, pp. 1096 - 1098
DOI: 10.1126/science.151.3714.1096
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Articles

Primary-Type Antibody Response in vitro

Tien-Wen Tao 1 and Jonathan W. Uhr 1

1 Irvington House Institute and Department of Medicine, New York University School of Medicine, New York

Organ cultures of lymph nodes obtained from nonimmunized rabbits were incubated with bacteriophage d, X174; as a result, 19S antibody was produced first, and then 7S antibody. Differences between this response and the secondary response to d? X174 induced in vitro suggest that the foriiier is a primary response.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
The Tissue Localization, Immunogenic, and Tolerance-Inducing Properties of Antigens and Antigen-Fragments.
G. L. Ada, C. R. Parish, G. J. V. Nossal, and A. Abbot (1967)
Cold Spring Harb Symp Quant Biol 32, 381-393
   Abstract »    PDF »
Primary Antibody Response Induced in vitro Among Cells from Normal Animals.
A. E. Bussard (1967)
Cold Spring Harb Symp Quant Biol 32, 465-475
   Abstract »    PDF »
Immunization of Normal Mouse Spleen Cell Suspensions in vitro.
R. I. Mishell and R. W. Dutton (1966)
Science 153, 1004-1006
   Abstract »    PDF »


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