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Science 11 February 1966:
Vol. 151. no. 3711, pp. 691 - 694
DOI: 10.1126/science.151.3711.691
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Articles

Synchronization of Mammalian Cells with Tritiated Thymidine

G. F. Whitmore 1 and S. Gulyas 1

1 Ontario Cancer Institute, 500 Sherbourne Street, Toronto, Ontario, Canada

Short exposures of mammalian cells to tritiated thymidine of high specific activity destroys the proliferative capacity of mammalian cells. Since the killing is limited to cells that have synthesized DNA in the presence of the labeled compound, an exposure duration of less than one generation can yield a synchronized population.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
The Direction of the Mitotic Axis in Human Epidermis.
H. PINKUS and R. HUNTER (1966)
Arch Dermatol 94, 351-354
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Science. ISSN 0036-8075 (print), 1095-9203 (online)