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Science 11 February 1966:
Vol. 151. no. 3711, pp. 687 - 689
DOI: 10.1126/science.151.3711.687

Articles

Mitochondrial DNA in Yeast and Some Mammalian Species

Gianmarco Corneo 1, Cyril Moore 1, D. Rao Sanadi 1, Lawrence I. Grossman 1, and Julius Marmur 1

1 Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York

Yeast DNA, in a cesium chloride density gradient, shows a minor or satellite band with a density lower than that of the main nuclear component. The DNA isolated from purified mitochondria of yeasts corresponds in density to this satellite band. In solution, this DNA more easily undergoes renaturation as compared to DNA from cell nuclei. The ease of this renaturation is presumably due to a homogeneity greater than that of nuclear DNA. Mitochondrial DNA isolated from several mammalian species has the same or higher density than nuclear DNA, but differs in its ready renaturability.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Mitochondrial DNA: Advances, Problems, and Goals.
M. M. K. Nass (1969)
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Cytoplasmic DNA from Petite Colonies of Saccharomyces cerevisiae: A Hypothesis on the Nature of the Mutation.
F. Carnevali, G. Morpurgo, and G. Tecce (1969)
Science 163, 1331-1333
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Biosynthesis of DNA by Isolated Mitochondria: Incorporation of Thymidine Triphosphate-2- C14.
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Nucleotide Sequence Repetition: A Rapidly Reassociating Fraction of Mouse DNA.
M. Waring and R. J. Britten (1966)
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