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Science 7 January 1966:
Vol. 151. no. 3706, pp. 97 - 99
DOI: 10.1126/science.151.3706.97
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Articles

Homograft Target Cells: Contact Destruction in vitro by Immune Macrophages

Gale A. Granger 1 and Russell S. Weiser 1

1 Department of Microbiology, University of Washington, School of Medicine, Seattle

Specific adherence of immune macrophages to monolayers of target cells is a passive phenomenon which represents only the first step in the mutually destructive interaction of immune macrophages and target cells. A specific hemagglutinin, responsible for specific adherence, was eluted from well-washed immune macrophages by heat treatment. The nature of the events in the interaction subsequent to adherence are unknown, but apparently demand the biosynthetic activities of the immune macrophage.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Cytophilic Antibodies in Man.
M. S. MITCHELL, M. B. MOKYR, G. T. ASPNES, and S. McINTOSH (1973)
Ann Intern Med 79, 333-339
   Abstract »    PDF »
Modification of Renal Allograft Rejection in Man.
C. B. Carpenter and J. P. Merrill (1969)
Arch Intern Med 123, 501-513
   Abstract »    PDF »
Cytotoxic Effects of Leukocytes Triggered by Complement Bound to Target Cells.
P. Perlmann, H. Perlmann, H. J. Muller-Eberhard, and J. A. Manni (1969)
Science 163, 937-939
   Abstract »    PDF »


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Science. ISSN 0036-8075 (print), 1095-9203 (online)