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Science 10 December 1965:
Vol. 150. no. 3702, pp. 1470 - 1472
DOI: 10.1126/science.150.3702.1470

Articles

Biosynthesis of Histones and Acidic Nuclear Proteins under Different Conditions of Growth

Lubomir S. Hnilica 1, Harvey A. Kappler 1, and Violette Schlatter Hnilica 2

1 Department of Biochemistry, University of Texas, M. D. Anderson Hospital and Tumor Institute, Houston
2 Baylor University College of Medicine, Houston 77025

The incorporation of uniformly labeled L-lysine-C14 into the normal and regenerating rat liver, into Novikoff hepatoma histones, and into acidic nuclear proteins was studied. In rat liver, different histone fractions incorporate labeled lysine to a different extent. Such differences become less obvious in regenerating liver, and they are even less so in Novikoff hepatoma. In the hepatoma cells the ratio of the biosynthesized acidic nuclear proteins to histones was altered.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Phosphorylation of Dipteran Chromosomes and Rat Liver Nuclei.
W. B. Benjamin and R. M. Goodman (1969)
Science 166, 629-631
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Science. ISSN 0036-8075 (print), 1095-9203 (online)