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Science 3 December 1965:
Vol. 150. no. 3701, pp. 1298 - 1303
DOI: 10.1126/science.150.3701.1298
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Articles

Rabbit 19S Antibodies with Allotypic Specificities of the a-Locus Group

G. W. Stemke 1 and R. J. Fischer 1

1 Department of Biology, Division of the Natural Sciences, and Department of Microbiology, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania

Activity of bacteriophage T4 neutralizing antiserums obtained 8 days after a primary immunization of rabbits with purified phage T4 is due to antibodies of the 19S (IgM) type. This neutralizing activity could be partially inhibited by treatment with excess antiserum directed against the a-locus group allotypic specificity carried by the whole rabbit serum.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Immunoglobulin M Allotypes of the Rabbit: Identification of a Second Specificity.
S. Sell (1966)
Science 153, 641-643
   Abstract »    PDF »
Antibody Active Sites and Immunoglobulin Molecules.
S. J. Singer and R. F. Doolittle (1966)
Science 153, 13-25
   Abstract »    PDF »


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Science. ISSN 0036-8075 (print), 1095-9203 (online)