Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Science 3 December 1965:
Vol. 150. no. 3701, pp. 1293 - 1294
DOI: 10.1126/science.150.3701.1293
Prev | Table of Contents | Next

Articles

Genetic Factors and Polypeptide Chain Subclasses of Human Immunoglobulin G Detected in Chimpanzee Serums

F. Paul Alepa 1 and William D. Terry 2

1 Arthritis and Rheumatism Branch, National Institute of Arthritis and Metabolic Diseases, Bethesda, Maryland
2 Immunology Branch, National Cancer Institute, Bethesda, Maryland

The Gm and Inv genetic factors, characteristic antigens of human immunoglobulin G, were detected in chimpanzee serums. All animals tested were Gm(a+, x—, bl—, b2—, b3+, b4+). Polymorphism was demonstrated for factors Gm(c), Inv(l), and Inv(b). Three of the subclasses of heavy polypeptide chains and both types of light polypeptide chains that are present in human immunoglobulin G were identified in chimpanzee serums.

To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)