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Science 26 November 1965:
Vol. 150. no. 3700, pp. 1181 - 1182
DOI: 10.1126/science.150.3700.1181
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Articles

Allograft Survival: Effect of Antiserums to Thymus Glands and Lymphocytes

Hiroshi Nagaya 1 and Herbert O. Sieker 1

1 Department of Medicine, Duke University Medical Center, Durham, North Carolina

Although antiserums to lymphocytes and thymus cells have similar effects on lymphocytes and thymocytes in vitro, the antiserum to thymus has more persistent lymphopenic effect in vivo and prolongs allograft survival time more markedly. Since only thymus glands of animals treated with antiserum to thymus showed depletion of small lymphocytes, antibody to thymic humoral factor may be operational.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Antilymphocyte Serum or Antithymus Serum.
H. Nagaya (1970)
Arch Intern Med 125, 499-502
   Abstract »    PDF »
Further Studies of Antilymphoid Sera in Clinical Renal Allotransplantation.
R. G. Shorter, G. A. Hallenbeck, C. F. Anderson, W. J. Johnson, J. H. DeWeerd, and G. K. Danielson (1970)
Arch Surg 100, 132-135
   Abstract »    PDF »
Antilymphoid Sera in Renal Allotransplantation.
R. G. Shorter, G. A. Hallenbeck, C. Nava, H. O. O'Kane, J. H. DeWeerd, and W. J. Johnson (1968)
Arch Surg 97, 323-329
   Abstract »    PDF »


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Science. ISSN 0036-8075 (print), 1095-9203 (online)