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Science 5 November 1965:
Vol. 150. no. 3697, pp. 779 - 781
DOI: 10.1126/science.150.3697.779
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Articles

Brain Transplantation: Prolonged Survival of. Brain after Carotid-Jugular Interposition

Robert J. White 1, Maurice S. Albin 1, George E. Locke 1, and Eugene Davidson 1

1 Neurosurgical Research Laboratories, Cleveland Metropolitan General Hospital, and Western Reserve University School of Medicine, Cleveland, Ohio 44106

Six isolated canine brains were successfully transplanted for 6 hours to 2 days to the cervical vasculature of dogs. Viability was shown by electrocortical activity and significant uptakes of oxygen and glucose, with production of carbon dioxide. Cerebral blood flows, temperatures, and pressures of the cerebral homograft were continuously monitored by way of an implantable recording module.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)