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Science 23 July 1965:
Vol. 149. no. 3682, pp. 429 - 431
DOI: 10.1126/science.149.3682.429
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Articles

Pseudouridine Formation: Evidence for RNA as an Intermediate

Samuel B. Weiss 1 and Jean Legault-Demare 1

1 Argonne Cancer Research Hospital, and Department of Biochemistry, University of Chicago, Chicago, Illinois 60637

Experiments with intact or lysed spheroplasts from Escherichia coli indicate that conditions which impair the DNA-directed synthesis of RNA, also prevent formation of pseudouridine. Studies with uridine-labeled RNA support the concept that RNA may be a direct intermediate for pseudouridine synthesis.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Enzymatic Modification of Transfer RNA.
D. Soll (1971)
Science 173, 293-299
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Human Pyrimidine Metabolism.
S. M. Weissman (1966)
JAMA 195, 27-30
   Abstract »    PDF »


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