Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Site Tools

  • AAAS
  • Subscribe
  • Feedback

Site Search

Search Advanced

Science 2 July 1965:
Vol. 149. no. 3679, pp. 72 - 73
DOI: 10.1126/science.149.3679.72
Prev | Table of Contents | Next

Articles

Lipase: Localization in Adipose Tissue

Merle S. Moskowitz 1 and Audrey A. Moskowitz 1

1 Department of Pathology, University of Colorado Medical Center, Denver 20

Certain problems usually associated with the histochemistry of lipases are obviated by a technique that utilizes the endogenous blood chylomicrons and the cellular stores of triglyceride as substrates for the histochemical demonstration of lipolytic enzyme activity in situ. In spreads of mesenteric adipose tissue, the technique makes it possible to distinguish between lipoprotein lipase activity at sites in the capillaries and lipolysis occurring in the adipocytes. The selective anatomic lolization of the lipase reaction correlated with the functional state of the tissue, and the absence of reaction product in control mesenteries from starved mice or in heat-inactivated controls, support the validity of this histochemical reaction.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Type III Hyperlipoproteinemia: Diagnosis, Molecular Defects, Pathology, and Treatment.
H. B. BREWER Jr., L. A. ZECH, R. E. GREGG, D. SCHWARTZ, and E. J. SCHAEFER (1983)
Ann Intern Med 98, 623-640
   Abstract »    PDF »


To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)