Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Science 25 June 1965:
Vol. 148. no. 3678, pp. 1746 - 1747
DOI: 10.1126/science.148.3678.1746
Prev | Table of Contents | Next

Articles

Radiation Resistance in Lipovirus-Altered Human Cells

John B. Little 1 and R. Shihman Chang 1

1 Departments of Physiology and Microbiology, Harvard School of Public Health, Boston, Massachusetts

Human cells altered by infection with the "lipovirus," a transmissible cytopathic agent, are highly resistant to ionizing radiation. Whereas about 500 roentgens will inhibit cell multiplication in normal cells, more than 500,000 roentgens are required to produce a similar effect in the altered cells. This gross change in cellular radiosensitivity may provide a useful system for studying in vitro the mechanisms of inhibition of cell division by radiation.

To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)