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Science 18 June 1965:
Vol. 148. no. 3677, pp. 1591 - 1592
DOI: 10.1126/science.148.3677.1591

Articles

Specificity of Macroglobulin Antibody Synthesized by the Normal Human Fetus

Wallace V. Epstein 1

1 Rheumatic Disease Group, Department of Medicine, University of California, San Francisco Medical Center, San Francisco

The umbilical cord blood of 47 out of 54 normal human infants contains hemagglutinating activity directed toward cells coated with a type-L Bence-Jones protein. This hemagglutinating material, in some instances, is present in cord blood in the absence of such activity in the maternal blood. Ultracentrifugation of cord serum in a sucrose gradient shows that the activity is associated with the macroglobulin fractions.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Allergy Review : Immunologic Aspects of the Allergic Infant: A Review with Comments on Recent Developments.
T. L. Nelson (1966)
Clinical Pediatrics 5, 191-196
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Science. ISSN 0036-8075 (print), 1095-9203 (online)