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Articles
Polymorphism of Human Lactate Dehydrogenase Isozymes
1 National Institute of Arthritis and Metabolic Diseases, National Institutes of Health, Bethesda, Maryland
Of 1200 individuals screened, four had variant erythrocyte lactate dehydrogenases. Three of these, identical electrophoretically to the Mem-1 described by Kraus and Neely, were heterozygous variants involving the a-locus. The fourth, involving the b-locus, appears to be the first example in man of a homozygous variant.
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Science. ISSN 0036-8075 (print), 1095-9203 (online)