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Science 30 April 1965:
Vol. 148. no. 3670, pp. 642 - 644
DOI: 10.1126/science.148.3670.642
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Articles

5-Hydroxytryptamine in Single Neoplastic Mast Cells: A Microscopic Spectrofluorometric Study

Lucas S. Van Orden 1, Itamar Vugman 1, and Nicholas J. Giarman 1

1 Department of Pharmacology, Yale University School of Medicine, New Haven, Connecticut

5-Hydroxytryptamine, catecholamines, and histamine in mast cells can be distinguished by fluorescence microscopy. Microscopic spectrofluorometry can be used to estimate 5-hydroxytryptamine in single neoplastic mast cells grown in vitro, and to study the effect of reserpine on these cells.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Serotonin Producing Neuroepithelial Bodies in Rabbit Respiratory Mucosa.
J. M. Lauweryns, M. Cokelaere, and P. Theunynck (1973)
Science 180, 410-413
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Science. ISSN 0036-8075 (print), 1095-9203 (online)