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Science 23 April 1965:
Vol. 148. no. 3669, pp. 513 - 516
DOI: 10.1126/science.148.3669.513
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Articles

Glucose-6-Phosphatase: Reexamination of the RNA-Induced Activity in Mouse Ascites Tumor Cells

M. C. Niu 1

1 Department of Biology, Temple University, Philadelphia, Pennsylvania

The glucostat method for the measurement of glucose released by glucose-6-phosphatase has been reexamined; it is accurate and sensitive enough to measure glucose-6-phosphatase activity in mouse ascites tumor cells. In seven different experiments, treatment with RNA from liver led to increases in enzyme activity varying between 125 to 200 percent. The activity of induced enzyme is optimum from pH 6 to 6.4.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)