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Science 16 April 1965:
Vol. 148. no. 3668, pp. 383 - 385
DOI: 10.1126/science.148.3668.383
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Articles

Hybrid Antibody Molecules with Allotypically Different L-Polypeptide Chains

Mart Mannik 1 and Henry Metzger 1

1 National Institute of Arthritis and Metabolic Diseases, Bethesda, Maryland

Isolated L-chains with either the A4 or the A5 allotypic markers from rabbit antibodies to 2,4-dinitrophenyl determinant recombine at random with antibody H-chains in the presence or absence of the hapten to produce hybrid precipitating antibody molecules.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)