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Science 2 April 1965:
Vol. 148. no. 3666, pp. 83 - 85
DOI: 10.1126/science.148.3666.83
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Articles

Sex Chromatin in Newborns: Presumptive Evidence for External Factors in Human Nondisjunction

Arthur Robinson 1 and Theodore T. Puck 1

1 Departments of Biophysics and Pediatrics, University of Colorado Medical Center, Denver 80220

An incidence of 0.6 percent of sex-chromosome aberrations in newborns was found during a 5-month period, while no aberrations occurred in similar populations before and after this period. Down's syndrome also exhibited an elevated frequency during this same critical interval. A severe rubella epidemic may have influenced this pattern.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Chromosomal Abnormality in the Newborns of Hepatitis B Surface Antigen (HBsAg) Carrier Mothers.
R. C. Jhaveri, R. S. Verma, W. Rosenfeld, D. J. Salazar, H. Dosik, and H. E. Evans (1980)
Clinical Pediatrics 19, 66-68
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Turner-Mongolism Polysyndrome: Review of the First Eight Known Cases.
M. M. Villaverde and J. A. Da Silva (1975)
JAMA 234, 844-847
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Down and Klinefelter Syndromes (48, XXY, G + ) in a Young Man: Cytogenetic, Endocrine, and Testicular Steroidogenesis Studies.
H. R. Nankin, J. B. Talbott, H. Oshima, D.-F. F. Fan, S. F. Pan, and P. Troen (1974)
Arch Intern Med 134, 352-358
   Abstract »    PDF »
A Serum Antigen (Australia Antigen) in Down's Syndrome, Leukemia, and Hepatitis.
B. S. BLUMBERG, B. J. S. GERSTLEY, D. A. HUNGERFORD, W. T. LONDON, and A. I. SUTNICK (1967)
Ann Intern Med 66, 924-931
   Abstract »    PDF »
New Hope for the Mentally Retarded.
J. R. E. (1965)
Ann Intern Med 63, 1145-1150
   Abstract »    PDF »
Rubella Epidemic, 1964: Effect on 6,000 Pregnancies: I. Preliminary Clinical and Laboratory Findings Through the Neonatal Period: A Report From the Collaborative Study on Cerebral Palsy.
J. L. SEVER, K. B. NELSON, and M. R. GILKESON (1965)
Arch Pediatr Adolesc Med 110, 395-407
   Abstract »    PDF »


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Science. ISSN 0036-8075 (print), 1095-9203 (online)