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Science 26 March 1965:
Vol. 147. no. 3665, pp. 1591 - 1592
DOI: 10.1126/science.147.3665.1591
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Articles

Involvement of Thymus in Immune Response of Rabbits to Somatic Polysaccharides of Gram-Negative Bacteria

Maurice Landy 1, Ronald P. Sanderson 1, Michael T. Bernstein 1, and Edwin M. Lerner II 1

1 Laboratories of Immunology and of Germfree Animal Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland

Plaque-forming cells elaborating antibody specific for Salmonella enteritidis somatic antigen have been demonstrated in the thymus of rabbits 5 days after a single systemic injection of a minute amount of this bacterial polysaccharide. A marked decrease in organ weight and loss of thymic cellularity was also seen, and was most pronounced at the time when antibody-forming cells made their appearance.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
The Thymus in Infants With Perinatal Telencephalic Leukoencephalopathy.
A. Leviton, F. H. Gilles, and G. F. Vawter (1978)
Arch Neurol 35, 377-381
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Science. ISSN 0036-8075 (print), 1095-9203 (online)