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Science 12 February 1965:
Vol. 147. no. 3659, pp. 753 - 754
DOI: 10.1126/science.147.3659.753

Articles

Micropuncture Study of Inulin Absorption in the Rat Kidney

Yehuda Gutman 1, Carl W. Gottschalk 1, and William E. Lassiter 1

1 Department of Medicine, University of North Carolina, School of Medicine, Chapel Hill

By means of a microinjection technique, inulin-carboxyl-C14 or inulin-methoxy-H3 was injected into single proximal tubules of the rat at various urine flow rates. Urine collected separately from the two kidneys showed negligible amounts of inulin activity on the noninjected side, thus demonstrating directly that there is no significant reabsorption of inulin by the renal tubular epithelium under these conditions.


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Ann. Pharmacother. 42, 1749-1757
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