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Science 12 February 1965:
Vol. 147. no. 3659, pp. 747 - 748
DOI: 10.1126/science.147.3659.747
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Articles

Probiotics: Growth-Promoting Factors Produced by Microorganisms

Daniel M. Lilly 1 and Rosalie H. Stillwell 1

1 Department of Biology, St. John's University, Jamaica, New York

Several species of protozoa, during their logarithmic phases of growth, produce substances that prolong the logarithmic phase in other species. The effect is not as striking as the inhibition of growth caused by antibiotics, but a consistent 50-percent increase in growth has been obtained with Tetrahymena pyriformis in response to a factor produced by Colpidium campylum.


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Probiotics ameliorate the hydrogen peroxide-induced epithelial barrier disruption by a PKC- and MAP kinase-dependent mechanism.
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Probiotics in Primary Care Pediatrics.
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Effects of a Probiotic Strain of Enterococcus faecium on the Rate of Natural Chlamydia Infection in Swine.
M. Pollmann, M. Nordhoff, A. Pospischil, K. Tedin, and L. H. Wieler (2005)
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A Special Fondness for Lactobacilli.
G. W. Tannock (2004)
Appl. Envir. Microbiol. 70, 3189-3194
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Probiotic Bacterium Prevents Cytokine-induced Apoptosis in Intestinal Epithelial Cells.
F. Yan and D. B. Polk (2002)
J. Biol. Chem. 277, 50959-50965
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Probiotics, prebiotics, and synbiotics--approaching a definition.
J. Schrezenmeir and M. de Vrese (2001)
Am. J. Clinical Nutrition 73, 361S-364
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Taxonomy and important features of probiotic microorganisms in food and nutrition.
W. H Holzapfel, P. Haberer, R. Geisen, J. Bjorkroth, and U. Schillinger (2001)
Am. J. Clinical Nutrition 73, 365S-373
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