Simian Virus 40: Isolation of Two Plaque Types
John L. Riggs 1 and
Edwin H. Lennette 1
1 Viral and Rickettsial Disease Laboratory, California State Department of Public Health, Berkeley 4
Two different morphological plaque types of simian virus 40 were isolated from three of six strains. Increased uptake of neutral red gave one type of plaque a uniform red appearance, whereas the center of the other remained unstained. The viruses showed stability of plaque morphology on passage in tissue culture; cross neutralization studies identified both as simian virus 40.