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Science 25 December 1964:
Vol. 146. no. 3652, pp. 1681 - 1682
DOI: 10.1126/science.146.3652.1681
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Articles

Allergic Encephalomyelitis: A Hyperacute Form

Seymour Levine 1 and Eugene J. Wenk 1

1 Pathology Department, New York Medical College Center for Chronic Disease, Bird S. Coler Hospital, Welfare Island. New York, New York

The hyperacute form of allergic encephalomyelitis is characterized by its short incubation period, 100 percent incidence, overwhelming severity, and high mortality and by the massive quantities of polymorphonuclear neutrophils, fibrin, and edema fluid which infiltrate the central nervous system. The hyperacute form has been produced with the aid of aqueous pertussis vaccine as an adjuvant. This is the first reproducible laboratory model for human acute necrotizing hemorrhagic encephalopathy.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
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Allergic Encephalomyelitis: New Form Featuring Polymorphonuclear Leukocytes.
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Science. ISSN 0036-8075 (print), 1095-9203 (online)