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Science 18 December 1964:
Vol. 146. no. 3651, pp. 1587 - 1588
DOI: 10.1126/science.146.3651.1587
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Articles

Methylurea and Acetamide: Active Reabsorption by Elasmobranch Renal Tubules

Bodil Schmidt-Nielsen 1 and Lawrence Rabinowitz 1

1 Department of Biology, Western Reserve University, Cleveland, Ohio, and Department of Physiology, University of North Carolina, Chapel Hill

The renal tubules of the shark actively reabsorb urea. They also can reabsorb acetamide and methylurea, but there is no evidence for active reabsorption of thiourea. The specificity of the transport system thus appears to be different from the urea secretory system in the frog in which thiourea is secreted but acetamide and methylurea are not secreted.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Significance of urea transport: the pioneering studies of Bodil Schmidt-Nielsen..
J. P. Kokko and J. M. Sands (2006)
Am J Physiol Renal Physiol 291, F1109-F1112
   Abstract »    Full Text »    PDF »
Urea transport in kidney brush-border membrane vesicles from an elasmobranch, Raja erinacea.
R. L. Morgan, P. A. Wright, and J. S. Ballantyne (2003)
J. Exp. Biol. 206, 3293-3302
   Abstract »    Full Text »    PDF »
Differential branchial and renal handling of urea, acetamide and thiourea in the gulf toadfish Opsanus beta: evidence for two transporters.
M. McDonald, C. Wood, Y Wang, and P. Walsh (2000)
J. Exp. Biol. 203, 1027-1037
   Abstract »    PDF »


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Science. ISSN 0036-8075 (print), 1095-9203 (online)