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Science 6 November 1964:
Vol. 146. no. 3645, pp. 778 - 779
DOI: 10.1126/science.146.3645.778
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Articles

Polyoma Virus: Production in Bacillus subtilis

K. E. Bayreuther 1 and W. R. Romig 2

1 Division of Biology, California Institute of Technology, Pasadena
2 Department of Bacteriology, University of California, Los Angeles

Particles of complete polyoma virus are produced in competent Bacillus subtilis incubated with DNA isolated from purified, conventionally grown polyoma virus. The virus grown in B. subtilis is biologically identical to polyoma virus produced by animal cells. Quantitative parameters of the system have been established, and fluctuation tests indicate that viral replication occurs within the infected bacteria.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Multiple Aminoacyl-RNA Synthetase Systems and the Genetic Code in Neurospora.
W. E. Barnett and J. L. Epler (1966)
Cold Spring Harb Symp Quant Biol 31, 549-555
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Antibody Induction and Tolerance.
O. Smithies (1965)
Science 149, 151-156
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