Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Site Tools

  • AAAS
  • Subscribe
  • Feedback

Site Search

Search Advanced

Science 25 September 1964:
Vol. 145. no. 3639, pp. 1449 - 1450
DOI: 10.1126/science.145.3639.1449
Prev | Table of Contents | Next

Articles

Sulfate Transport in Human Red Cells: Inhibition by Some Uncouplers of Oxidative Phosphorylation

Akira Omachi 1

1 Department of Physiology, University of Illinois College of Medicine, Chicago

Release of inorganic sulfate from human erythrocytes is depressed in the presence of 2,4-dinitrophenol (5 x 10-4M) or dicumarol (5 x 10-4M). This effect cannot be readily attributed to uncoupling of phosphorylation from respiration, since the study was conducted with cells that metabolize principally by anaerobic means and since the effect was not influenced by iodoacetic acid. A more reasonable explanation may be that permeability of the erythrocyte membrane to anions may be reduced by these agents.

To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)